Biological Sciences (BIOS)

BIOS 10010 The Climate Crisis: Intersection between Biology and Christianity (3 Credit Hours)

The Climate Crisis will explore how science and religion intersect in their analyses of climate change. We will emphasize two questions: (1) How has climate change over the past 30 years impacted biological organisms and ecosystems? (2) How ought Catholics respond to climate change, and how does such a response inform your own response? Readings will be drawn from a basic science textbook, writings from recent popes and from other Christian writers. The class sessions will be active, and focused on discussion and activities. This course is open to all, and is inspired by the UND mission that various lines of Catholic thought may intersect with all forms of knowledge.

Satisfies the following University Core Requirements: WKCD-Core Cathol & Disciplines

BIOS 10050 Biodiversity Studies in the Anthropocene (3 Credit Hours)

Biodiversity encompasses many more facets than simply the number of species in a location. This course will examine these different types of biodiversity and the ways in which scientists use cutting-edge technologies, such as AI, to study biodiversity. Students will also explore the many challenges facing species alive today and consider the complexity of equitable and ethical biodiversity conservation. Classes will combine lecture with hands-on learning activities using specimens from the Museum of Biodiversity and real datasets to build data analysis skills and critical thinking. Students will apply these skills to develop hypotheses on biodiversity-related questions and interrogate data that they collect on local field trips.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10091 Human Genetics, Evolution, and Society (3 Credit Hours)

For achieving a qualifying score on the appropriate Advanced Placement (AP) or International Baccalaureate (IB) exam, students earn credit for this course as the exam credit equivalent of BIOS 10101 . This course will address fundamental biological principles using the two cornerstones of modern biology: genetics and evolution. Elementary chemistry, cell theory, reproduction, and development will also be covered. The emphasis, however, will be on human genetics and will include such topics as the cause and effects of genetic abnormalities, the genetic basis of intelligence and skin color, genes and cancer, and elementary population genetics. The state of "genetic engineering" research, the recombinant DNA controversy (including the implications of this kind of research on society and the individual) will be presented.

BIOS 10097 Ecology and Environmental Issues (3 Credit Hours)

For achieving a qualifying score on the appropriate International Baccalaureate (IB) exam, students earn credit for this course as the exam credit equivalent of BIOS 10107. Emphasis will be placed upon today's ecological and environmental problems and the possible effect they may have upon the future evolution of life on Earth. Topics will generally include an overview of the theory of evolution and a discussion of ecological principles as observed at the population, community, and ecosystem levels. The influence of cultural and political factors will also be discussed. Each academic year, one or more sections will be offered; some may be individually subtitled, allowing for one-time presentation of specific topics within the context of "environment and evolution;" in addition to multiple-semester presentations of a specific topic (e.g., Evolutionary Ecology, Freshwater and Society, Environmental Issues and Solutions). Summer. This course counts as general elective credit only for students in the College of Science.

BIOS 10098 Credit By Exam - Intro Biology (4 Credit Hours)

Students receiving a 5 on the Biology AP I examination or an IB grade of 7, receive credit fully equivalent to BIOS 10161 and 11161 and BIOS 10162 and 11162, i.e., the first year sequence of Biological Sciences I and II with laboratories designed for science majors. For those students who choose not to waive AP or IB credit, BIOS 10098 and BIOS 10099 combined will be accepted as a prerequisite for all upper-level biology courses where BIOS 10161 and/or BIOS 10162 are the prerequisites. Students intending to apply to medical or other professional schools where AP science credit is not accepted, or where two semesters of general biology with laboratories at the college level are required, almost universally waive their AP credit at Notre Dame and take the classes for academic degree credit. In these cases, BIOS 10098 and BIOS 10099 will revert to non-degree credit on their final transcript, when replaced by 8.0 letter-graded degree credits of either BIOS 10161 and 11161, BIOS 10162 and 11162 or BIOS 20201 and 21201, BIOS 20202 and 21202 as determined by the requirements of their respective majors.

BIOS 10099 Credit By Exam - Intro Bio II (4 Credit Hours)

Students receiving a 5 on the Biology AP examination or an IB grade of 7, receive credit fully equivalent to BIOS 10161 + 11161 and BIOS 10162 + 11162, i.e., the first year sequence of Biological Sciences I and II with laboratories designed for science majors. For those students who choose not to waive AP or IB credit, BIOS 10098 and 10099 combined will be accepted as a prerequisite for all upper-level biology courses where BIOS 10161 and/or BIOS 10162 are the prerequisites. Students intending to apply to medical or other professional schools where AP science credit is not accepted, or where two semesters of general biology with laboratories at the college level are required, almost universally waive their AP credit at Notre Dame and take the classes for academic degree credit. In these cases, BIOS 10098/10099 will revert to non-degree credit on their final transcript, when replaced by 8.0 letter-graded degree credits of either BIOS 10161/11161 + 10162/11162 or BIOS 20201/21201 + 20202/21202 as determined by the requirements of their respective majors. Please see printed section of this bulletin (page 125) for a general statement pertaining to Biology Survey Courses.

BIOS 10101 Human Genetics, Evolution, and Society (3 Credit Hours)

This course will address fundamental biological principles using the two cornerstones of modern biology: genetics and evolution. Elementary chemistry, cell theory, reproduction, and development will also be covered. The emphasis, however, will be on human genetics and will include such topics as the cause and effects of genetic abnormalities, the genetic basis of intelligence and skin color, genes and cancer, and elementary population genetics. The state of "genetic engineering" research, the recombinant DNA controversy (including the implications of this kind of research on society and the individual) will be presented. Fall and spring.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10105 Molecular Basis of Disease (3 Credit Hours)

This course explores the genetic basis of disease with an understanding of Mendelian patterns of inheritance and gene expression. We will discuss the impacts of genetic technology in medicine, which includes topics in gene therapy and DNA testing. The study of infectious diseases is prefaced by a discussion of the proper functioning of the immune system. Antibiotic resistance, vaccine myths, and re-emerging disease are public health concerns addressed in this course.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10107 Ecology and Environmental Issues (3 Credit Hours)

Emphasis will be placed upon today's ecological and environmental problems and the possible effect they may have upon the future evolution of life on Earth. Topics will generally include an overview of the theory of evolution and a discussion of ecological principles as observed at the population, community, and ecosystem levels. The influence of cultural and political factors will also be discussed. Each academic year, one or more sections will be offered; some may be individually subtitled, allowing for one-time presentation of specific topics within the context of "environment and evolution;" in addition to multiple-semester presentations of a specific topic (e.g., Evolutionary Ecology, Freshwater and Society, Environmental Issues and Solutions). Summer. This course counts as general elective credit only for students in the College of Science.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10110 Biology and Society (3 Credit Hours)

Increased understanding of biological processes has fueled the development of new biotechnology. The course covers topics of current relevance, including the use of antibiotics, the development of genetically modified foods, genetic testing capabilities, stem cell technologies, cancer causes and treatments. Each topic is developed through reading assignments, instructor presentations, review of news media, and in class group interactions. A heightened awareness of the topic, and opposing viewpoints, will be developed through student debates and other in-class activities. Grading is based on class participation, online quizzes, assignments, and a final exam. <p> Note: this course is delivered fully online. The course design combines required live weekly meetings online with self-scheduled lectures, problems, assignments, and interactive learning materials. To participate, students will need to have a computer with webcam, reliable internet connection, and a quiet place to participate in live sessions.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10112 The Marine Environment (3 Credit Hours)

The world ocean makes up 97% of the planet's water and 99% of all living space on earth. Ocean systems and processes have a profound effect on our current and future well-being, yet the ocean remains mysterious to us in many ways. Humans have caused and continue to cause radical changes in ocean chemistry, physics, and biology. It is therefore more critical than ever for us to understand the mechanisms that undergird the physical and biological aspects of the world ocean. This class is divided into three parts: the first provides an introduction to oceanography - the physical aspects of the ocean. The second is an exploration of the incredibly diverse organisms that inhabit the ocean and how they interact with each other and their environment. The last section of the class focuses on human environmental impacts on the world ocean and how human societies and policies can best contribute to ocean health.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10115 Microbes and Man (3 Credit Hours)

The course will provide a survey of relationships between man and microorganisms. General information about microbial physiology, biochemistry, and ecology will support more detailed discussions of interesting topics in food, medical, and applied microbial biology. Included will be subjects of general and historical interest, as well as current newsworthy topics. The student should get a better understanding of the role of microorganisms in disease, the production of common foods, relevant environmental issues, and biotechnology.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10117 Fundamentals of Conservation Biology (3 Credit Hours)

This course is an introduction to the interdisciplinary field of conservation biology for non-majors. We will begin by reviewing how science works and doing a brief survey of life on Earth. We will then go over a brief history of life and conservation before delving into the science of ecology and what constitutes biodiversity. This will be followed by the current major threats to biodiversity, including habitat loss, overexploitation, climate change, and invasive species. Finally, we conclude with an overview of the various conservation methods for preserving biodiversity, including designating reserves, managing populations, and conserving resources. Over the course of the semester we will also cover the history of conservation in the United States as told through the lens of the National Parks system. Virtual lab activities will also bring an active-learning component to emphasize key lessons from lecture.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10119 Evolution and Society (3 Credit Hours)

Evolution is the cornerstone of modern biological sciences. This course will highlight evolution as well as ecology and biodiversity. Emphasis will placed on the evolution of animal behavior including human behavior. Sexual selection and its role in shaping many forms of life, including humans, will be extensively covered. Open classroom discussion is a central and required part of the course.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10161 Biological Sciences I (3 Credit Hours)

This is a two-semester course with three lectures and one three-hour laboratory a week for first-year students contemplating a career in biology, medicine, or related areas of life science. The first semester presents a description of biologically important molecules and then proceeds to cell structure, energy metabolism, and classical and modern genetics. The topics presented in the second semester in the context of modern evolutionary theory include biological diversity, ecology, and organismal physiology. BIOS 10161 and 10162 are not typical survey courses; they go into greater depth, especially in modern molecular biology. When followed by BIOS 20241 and BIOS 20250, they will provide biology and biochemistry majors, including premedical intents, with a thorough in-depth overview of basic concepts of modern biology.

Corequisites: BIOS 11161, BIOS 12161

Satisfies the following University Core Requirements: WKST-Core Science & Technology

Enrollment is limited to students with a major in Environmental Sciences or Environmental Sciences (Supp.).

BIOS 10162 Biological Sciences II (3 Credit Hours)

This is the second semester of a two-semester course for first year students contemplating a career in biology, medicine, or related areas of life science. The topics presented in the second semester in the context of modern evolutionary theory include biological diversity, ecology, and organismal physiology.

Prerequisites: BIOS 10161

Corequisites: BIOS 11162

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10169 Biology I: Big Questions Mod 1 (0 Credit Hours)

"Big Questions" is the fall introductory biology course for freshman and sophomore students. The hallmarks of the course include a conceptual and integrated approach to learning biology, emphasis on scientific practice, and teaching practices consistent with the way students learn. Eight professors will teach sections of introductory biology in the context of an interesting "big question" in their area of expertise. This contextual learning will allow students to comprehend how various levels of biology are needed to solve contemporary problems such as climate change, infectious diseases, and the origin of life. Students will also learn process skills and develop a framework to scaffold biological information into a whole. This will allow them to better retain knowledge to use in the second introductory course, Biology II: Molecules to Ecosystems, in the spring semester.

Corequisites: BIOS 10170, BIOS 10171, BIOS 11173

BIOS 10170 Biology I: Big Questions Mod 2 (0 Credit Hours)

Corequisites: BIOS 10171, BIOS 11173

Course may be repeated.

BIOS 10171 Biology I :Big Questions (3 Credit Hours)

This is the first in a two-course series that covers five key concepts in Biology - evolution; structure and function; information flow, exchange, and storage; pathways and transformations of energy and matter; and systems. Big Questions investigates these key biological concepts within the context of two "big questions" in modern Biology. For more information about course format and content see the Department of Biological Sciences homepage. Most students enroll concurrently in BIOS 11173 Biological Investigations Laboratory (1 CREDIT).

Corequisites: BIOS 11173

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10172 Biology II: Molecules to Ecosystems (3 Credit Hours)

This is the second course in the two-course Introductory Biology series. Molecules to Ecosystems provides an opportunity to master and integrate the five key biological concepts - evolution; structure and function; information flow, exchange, and storage; pathways and transformations of energy and matter; and systems. Throughout the course students are challenged to make connections among these concepts and apply them to their own biological questions. For more information about course format and content see the Department of Biological Sciences homepage. Most students enroll concurrently in BIOS 11174 Research Experience in Biology Laboratory (1 CREDIT).

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 10191 Biology's Impact in Our World (3 Credit Hours)

Students explore core principles in biology that are encountered on a daily basis in the news as they relate to changes in our lives and society in general. These are controversial issues that society is debating, because they affect social policy. Several foci emerge from this debate. First, what is the role of biotechnology on our lives? This includes issues with the widespread use of antibiotics and genetically modified foods, genetic testing, cancer treatment and pharmaceutical development. Second, what happens when biology challenges the beliefs and activities of people? This includes issues dealing with stem cell technology, the origin and evolution of life, the preservation of biodiversity, and human impact on the biosphere. Each week a different issue is investigated using a multifaceted approach to increase student awareness of the underlying controversy. First, a basic knowledge of the biological principle is pursued via in- and out-of-class lecture and readings. Next, in-class problem-solving and discussion of the controversy is undertaken. And finally, a student run debate is held to more fully appreciate the underlying reasoning and passion of opposing viewpoints.

Satisfies the following University Core Requirements: WKST-Core Science & Technology

Students in the College of Science college may not enroll.

BIOS 11161 Biological Sciences I - Lab (1 Credit Hour)

The laboratory sessions are an integral part of the lecture courses, which will complement the lectures. The lab sessions will also offer the student direct experience in using the scientific method and simultaneously introduce numerous biological and analytical techniques. In addition, students learn to present their findings during the course of the two semesters of laboratory as they would for a journal article or a scientific meeting (seminar and poster presentations).

Corequisites: BIOS 10161

BIOS 11173 Biological Investigations Laboratory (1 Credit Hour)

This course provides an opportunity to develop fundamental research skills used in the study of biological systems. The overall goal of this course is to help students learn to "think like a biologist", while developing a "toolbox" of techniques that can be applied to current research questions in biology. In this course, students acquire specific technical skills, including field insect collection; light microscopy; DNA isolation, PCR, and electrophoresis; bacterial transformation; and data analysis and graphing. Across the semester the students apply these skills in the context of open-ended biological problems and communicate the results of their experiments. Most students enroll concurrently in BIOS 10171 Biology I: Big Questions (3 CREDITS).

Corequisites: BIOS 10171

BIOS 11174 Research Experience in Biology Laboratory (1 Credit Hour)

This course challenges students to apply their biological research skills to a semester-long authentic research project. Over the semester, students develop their skills in technical protocols, experimental design and analysis, and scientific communication while creating biological knowledge in one of three ongoing research projects. Most students enroll concurrently in BIOS 10172 Biology II: Molecules to Ecosystems. See Section Notes for information about the specific research project in a particular section.

Corequisites: BIOS 10172

BIOS 20100 Brain Disorders and What We Can Do (1 Credit Hour)

The course will be composed of three weekly lectures for a total of 10 lectures. There are no prerequisites and no prior knowledge of the nervous system is required. The course will begin with an overview of the central nervous system, which students will learn basic cell structure (neuron vs. glia), brain nuclei and basic nervous system physiology such as action potential and neurotransmitter release. Following the teaching of the biological essentials, students will learn about the brain through readings, lectures, and discussions of the book, "The Brain that Changes Itself", written by Dr. Norman Doidge. This is not a standard text, but rather a series of case studies described by a psychiatrist. It is extremely well written and is meant to be approachable to non- experts of the field of neuroscience. Lectures and small group discussion will be the two main formats during each live class meeting. Video clips related to the course topic will be provided for asynchronous learning. By examining in detail several distinct neurological phenomena, students will gain perspective regarding the complexity of our nervous system.

BIOS 20201 General Biology A (3 Credit Hours)

Introduction to living organisms with emphasis on biological processes and principles. BIOS 20201 introduces biology to the student at the cellular level, covering such topics as important biological molecules, energy metabolism, and classical and modern genetics. BIOS 20201 and 20202, along with their concomitant laboratories (BIOS 21201 and 20202) constitute a traditional two-semester introduction to biology. This sequence covers more topics, but in less depth, than the former BIOS 155-156 or BIOS 10161-10162 and is designed to provide students with the necessary background for subsequent advanced biology courses and to help them prepare for MCATS. A prerequisite is a full year of college chemistry. In addition, organic chemistry is to be taken concurrently.

Prerequisites: CHEM 10122 or CHEM 10172 or CHEM 10182

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 20202 General Biology B (3 Credit Hours)

Introduction to living organisms with emphasis on biological processes and principles, and goes beyond the cellular level, with an emphasis on organismic physiology, evolution, diversity, and ecology. BIOS 20201 and 20202, along with their concomitant laboratories (BIOS 21201 and 21202) constitute a traditional two-semester introduction to biology. This sequence covers more topics, but in less depth, than BIOS 10161 and 10162 and is designed to provide students with the necessary background for subsequent advanced biology courses and to help them prepare for MCATS. A prerequisite is a full year of college chemistry. In addition, organic chemistry is to be taken concurrently.

Prerequisites: BIOS 20201 and (CHEM 10122 or CHEM 10171 or CHEM 10181)

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 20204 Introduction to Ecological Horticulture (1 Credit Hour)

Globally, the agricultural sector is the largest cause of habitat loss, aquifer depletion, and greenhouse gas emissions. The need to transform agricultural systems to meet the needs of the world's growing population while addressing these ecological impacts is one of the 21st century's grand challenges. This course will include principles, concepts and practices of sustainable food production including biodiversity, soil quality, and nutrient, water, pest and disease management, while focusing on a production culture that is environmentally regenerative. Every class meeting will involve experiential learning that will build students' skills in growing healthy food in a way that protects and restores the earth. This class will also address the environmental and social consequences of industrial farming and public health impacts of quality food accessibility in communities.

Prerequisites: (BIOS 10161 (may be taken concurrently) and BIOS 10162 (may be taken concurrently)) or (BIOS 20201 (may be taken concurrently) and BIOS 20202 (may be taken concurrently)) or (BIOS 10171 and BIOS 10172)

BIOS 20241 Molecular Cellular Biology (3 Credit Hours)

This course is intended for Biology Majors who have completed Classic and Molecular Genetics (BIOS 20250) but open to students in Neuroscience and Behavior, Biochemistry and Preprofessional Studies Majors who have the appropriate background. This course explores the structural and functional basis of cell biology, with specific emphasis on molecular mechanisms that regulate cellular activities involved in protein folding, biological membrane function, organelle biogenesis, vesicular transport, cell signaling, cell cycle control and mitosis. The course incorporates the experimental basis of concepts in cell biology and modern day applications of cell biology research in human disease. Course content provides essential foundations for MCAT and GRE exam preparation. The optional Molecular Cell Biology Research course (BIOS 27241) adds more exposure to modern Cell Biology topics.

Prerequisites: (CHEM 10172 or CHEM 10182) and BIOS 20250

Satisfies the following University Core Requirements: WKST-Core Science & Technology

Enrollment is limited to students with a major in Biological Sciences.

BIOS 20250 Classical and Molecular Genetics (4 Credit Hours)

This course is restricted to biological science, biochemistry, or neuroscience majors only. The course exposes students to classical and molecular genetics and demonstrates how these two approaches can combine to examine complex problems. The lecture is strongly weighted toward teaching students to solve genetic and molecular biological problems. The course is taught in a “flipped” format, where students watch recorded lectures and then come to class to apply the material in a variety of problems and exercises. Thus, a significant amount of time is spent helping students learn how to think like a geneticist, solving problems, and analyzing data. The course begins by exploring topics in classical genetic principles, such as Mendelian genetics, mitosis and meiosis, genetic linkage, chromosome structure and abnormalities. The course then builds on this foundation by discussing the “central dogma” of DNA replication, RNA transcription, and protein translation. The course then moves into learning how the tools of molecular biology (DNA sequencing, hybridization techniques, DNA cloning, generating mutants and transgenic animals) are used to study fundamental processes in genetics, gene regulation, and development. Throughout, the course employs examples in both model organisms and human diseases to demonstrate the relevance of the concepts being discussed. Students are presented with the techniques to apply underlying genetic principles through problem solving and data analysis. The large amount of time that is spent in class learning how to solve problems and analyze data prepares the student for exams that are based on the types of problems that are practiced in class and assigned to be worked on in small groups. The laboratory gives the students hands-on experience in a number of genetic and molecular techniques and demonstrates how many of the concepts covered in lecture are applied in generating a cohesive genetic picture.

Prerequisites: BIOS 10161 or BIOS 20201 or BIOS 10172

Enrollment is limited to students with a program in Biochemistry, Biological Sciences, Environmental Sciences or Neuroscience and Behavior.

BIOS 20251 Mendelian & Molecular Genetics (4 Credit Hours)

This course deals with two major areas. The first area is classical genetics: Mendelian principles, chromosome mechanics, linkage and recombination, and chromosomal mutations. The second area is molecular genetics: DNA replication, RNA transcription, protein translation, recombinant DNA techniques, the nature of the gene and regulation of gene expression. However, these areas are not mutually exclusive and often the same concept is applied at different times in the course. The integration of topics at different points throughout the course will help to reinforce the material for the student and demonstrate how our understanding of genetics has been built over time. Pre-requisites: Students are required to have completed a year-long Introductory Biology sequence prior to taking this genetics course.

BIOS 20300 Local Flora (1 Credit Hour)

This is a field-based course that explores the rich biodiversity of plant life in northern Indiana. Through hands-on experience in a diverse array of field sites, you will be introduced to various plant communities and learn to identify the plants within them. Plant communities and species distributions reflect patterns and processes as ancient as plate tectonics and as recent as glaciers and European settlement. They reflect the influence of temperature and moisture patterns as well as competition within and among plant species. They are shaped by interactions with animals, insects, and disease, as well as the actions of humans.Plants are the foundation of every terrestrial habitat, but are often overlooked. By developing a greater familiarity with plant communities and skills for identification, you will be better prepared to appreciate natural habitats, participate in conservation work, and conduct field research.

BIOS 20303 Fundamentals of Genetics (3 Credit Hours)

An elementary course dealing with the principles of variation and inheritance in plants and animals, with special reference to humans. Designed primarily for junior preprofessional students. Spring.

Prerequisites: BIOS 10161 or BIOS 20201

Satisfies the following University Core Requirements: WKST-Core Science & Technology

BIOS 20344 Transfer Physiology (4 Credit Hours)

Transfer physiology

BIOS 20401 Fundamentals of Biological Anthropology (3 Credit Hours)

This course approaches human evolution from a theoretical point of view that combines both biological and cultural processes into a cohesive bio-cultural model. It begins by tracing the development of modern evolutionary theory and the place of evolutionary studies in anthropology, especially in the sub-field of bioanthropology. These concepts provide the framework for understanding the many lines of evidence that anthropologists use to explore and explain human evolution. These include studies of our primate relatives, through the intricacies of the fossil record, to archaeological evidence for the invention of material culture from the simplest stone tools to the complex cultural world that we live in today. Modern human variation can only be explained as the result of evolutionary forces acting on the complex interplay of biology and culture over millions of years. We continue to be affected by these forces, and this course not only provides information about where we came from, it also provides the scientific backgrounds to help us understand where we might be going as our species continues to evolve.

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 20450 Neuroscience and Behavior (3 Credit Hours)

This course is intended to provide a broad introduction to the field of neuroscience and behavior, from the level of molecules flowing across cell membranes up to complex human cognition. It is intended primarily for sophomores and required of all Neuroscience and Behavior majors. The associated laboratory is also required an may be taken concurrently or at a later time.

Prerequisites: (BIOS 10161 and BIOS 11161) or (BIOS 20201 and BIOS 21201)

Enrollment is limited to students with a program in Neuroscience and Behavior.

BIOS 20480 Intro to Dyn Sys for Scientist (3 Credit Hours)

This is a one-semester course introducing students to linear algebra and ordinary differential equations by way of their scientific usage. The course serves as a gateway to more advance mathematical methods that are commonly used in contemporary scientific studies and their literature. Students will learn how to take a mathematical approach to various scientific problems, solve the resulting equations, and interpret the mathematical solution in the original context. There will be course projects and some usage of computing software. Topics include matrix algebra, eigenvalues and eigenvectors, vector-valued functions, linear and non-linear systems of differential equations, and phase portraits. The scientific topics include age-structured population growth, the Richardson's theory of war, and infectious disease modeling.

Satisfies the following University Core Requirements: WKQR- Core Quantitat Reasoning

BIOS 21201 Transfer BIOS Lab Non BIOS 1 (1 Credit Hour)

Transfer BIOS Lab for Non Bios Majors.

BIOS 21202 Transfer BIOS Lab Non BIOS 2 (1 Credit Hour)

Transfer BIOS Lab for Non-Bios Majors.

BIOS 21241 Molecular Cell Biology Research (2 Credit Hours)

This cell biology laboratory, reserved exclusively for BIOS majors, is an investigative, project-based laboratory designed to expose students to a bona fide research experience involving the development and application of critical thinking skills to solve complex research problems. Working in groups of four to six, students will devote themselves to tackling self-chosen research projects reviewed and approved by course instructors. The culmination of the laboratory experience ends when students formally prepare and present their findings in a poster-style scientific meeting.

Prerequisites: BIOS 20241 (may be taken concurrently)

BIOS 21250 Classical and Molecular Genetics Laboratory (2 Credit Hours)

In this laboratory course, students will characterize mutations that cause retinal degeneration in the fruit fly, <i>Drosophila Melanogaster</i>, in a series of related experiments comprising a semester-long study. The labs will be broken into two major sections, starting with the genetic characterization of a mutation, followed by the molecular characterization of the altered gene causing that mutation. This directed research project will be presented in two drafts of a complex research paper. Some work outside the four-hour lab period will be required. Fall.

Prerequisites: BIOS 20250 (may be taken concurrently)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 21303 Fundamental Genetics Laboratory (1 Credit Hour)

This laboratory provides experience in genetics and molecular biology experimentation and analysis in a smaller scale project than the fall genetics lab. The course is a semester-long research project, so this is not a regular lab course. Any life science major can do well in this course. You will use Mendelian and molecular genetics to characterize a gene that causes a disease in an animal model. You will write a paper in a mentored experience and learn about molecular genetics research through this process. By the end of the course, you will be able to: 1. Demonstrate proficiency in essential laboratory techniques in molecular biology and genetics 2. Demonstrate proficiency in scientific writing and clearly articulate scientific concepts 3. Develop open, honest, and empathetic communication and collaboration skills to work effectively with a lab partner 4. Develop confidence and research competence to pursue undergraduate research (or a research job, if you are a senior) after the conclusion of the course

Prerequisites: BIOS 20303 (may be taken concurrently)

BIOS 21344 Transfer Physiology Lab (0 Credit Hours)

Transfer physiology lab.

BIOS 23101 Professional Development for the Environmental Sciences (1 Credit Hour)

Professional Development for the Environmental Sciences is a seminar course that will help students in the major get the most out of their undergraduate experience as they move through the program. The primary purpose is to orient students early in their college career to the many opportunities that exist both in and outside the university, and to help their career discernment and development. Students will also be given opportunities to explore relevant issues and access information that will help guide planning for their major, both inside and outside the classroom as well as careers beyond university. The topics covered during the course will range from an exploration of the major differences among sub-disciplines within Environmental Sciences, to more practical aspects of planning and achieving milestones in the development of a career, be it in graduate, medical, or law school, or public service and private industry. Students will also have the opportunity to meet invited speakers from outside the university along with a number of faculty from the various departments and colleges relevant to the major that would provide the foundation of opportunities, such as undergraduate research and graduate level courses to consider taking. By the end of the course, students will be able to (1) identify what career options are available to those with an environmental sciences career; (2) articulate what aspects of an environmental sciences career they are most interested, and (3) plan out what are the critical steps that need to be taken to prepare for a post-graduate career in the environmental sciences.

BIOS 27241 Molecular Cell Biology Research-Special Studies. (2 Credit Hours)

Prerequisites: BIOS 20241 (may be taken concurrently)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 30301 Embryology (3 Credit Hours)

Overview of the embryology and histology of the developing organism with an emphasis on the clinical aspects. Content similar to BIOS 30342.

Prerequisites: BIOS 10162 or BIOS 10172 or BIOS 30344

Enrollment is limited to students with a major in Pre-Health Studies (Supp.), Science- Business or PreProfessional.

BIOS 30305 Evolution (3 Credit Hours)

The mechanisms and processes involved in the production of life as we know it today, as well as a discussion on the impact current events may have upon life in the future.

Prerequisites: (BIOS 10162 or BIOS 20202 or BIOS 20250 or BIOS 20303)

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 30310 The History of Life (3 Credit Hours)

This course explores the origin, history, and systematics of life on Earth, starting from hypotheses examining life's origin(s) and including current thinking concerning the systematic relationships of organisms and the evolution of humans. The class will be taught primarily from a macroevolutionary perspective. BIOS 30310 therefore represents the complement to BIOS 30305 (Evolution), which concentrates on processes generating gene frequency changes within populations (i.e., microevolution). Fall.

Prerequisites: BIOS 10162 or BIOS 20202

BIOS 30312 General Ecology (3 Credit Hours)

The study of populations and communities of organisms and their interrelations with the environment. Fall and spring.

Prerequisites: (BIOS 10162 or BIOS 20202)

Enrollment is limited to students with a major in Biological Sciences, Environmental Sciences or Environmental Sciences (Supp.).

BIOS 30318 Introduction to Biocomputing (3 Credit Hours)

Modern biology, as well as biochemistry and biophysics, relies significantly on computation. The volumes of data generated by modern lab and field research commonly require greater capacity and more sophisticated algorithms for reformatting, filtering, and analyzing than are available in traditional spreadsheet software. As a result, an efficient and productive scientist must possess, at least basic, biocomputational skills. Often these requisite skills include the ability to navigate the Unix Shell environment, to understand and implement existing software tools, and to use a scripting language for data processing and analysis. This course will provide students with the knowledge and experience required to apply these important tools in diverse contexts. Approximately one-third of the course will focus on using the Unix Shell environment with an introduction to bioinformatics approaches. The remaining two-thirds of the course will build the students' skills in the use of the R scripting language and applications in statistics and dynamic modeling. No previous coding experience is required of students in this course

Corequisites: BIOS 32318

BIOS 30325 Plants, Society and the Environment (3 Credit Hours)

Plants have provided food, medicine, fuel, and raw materials for humans throughout our history. Concurrently, humans have modified the distribution, diversity and utility of plants for our benefit in ways that are often unsustainable. Many of the grand environmental and societal challenges of today and tomorrow involve our interactions with plants and the pivotal roles they play in our natural and modified environments. The goal of this course is to provide foundational knowledge about the biology and diversity of plants. This includes learning the basics of plant anatomy and physiology and the ecology and evolutionary history of plants. This knowledge is then utilized to discuss plants as sources of food, commercial products, medicines and toxins in the past, present and future of human society."

Prerequisites: (BIOS 20241 or BIOS 30341 (may be taken concurrently)) and (BIOS 20250 or BIOS 20303)

Enrollment is limited to students with a major in Biological Sciences, Environmental Sciences or Environmental Sciences (Supp.).

BIOS 30338 Advanced Neurobiology (3 Credit Hours)

This course is designed for students interested in the molecular and cellular aspects of neurobiology. It starts by defining what neurons and glia cells are and goes further by explaining how neural networks form, work and how disease-causing mutations disrupt these processes, as shown in animal models or human patient cells used as models for autism and schizophrenia. It will provide an overview of molecular and cellular neuroscience by focusing on several key topics, such as nervous system development, cytoskeletal regulation and neurite formation, axonal pathfinding, synapse formation and function, voltage-gated ion channels, neurotransmitter receptors, neurotransmitter release, neuronal gene expression and more.

Prerequisites: (BIOS 10161 or BIOS 10171 or BIOS 20201) and (BIOS 10162 or BIOS 10172 or BIOS 20202) and (BIOS 20241 or BIOS 30341 or BIOS 10101 or BIOS 10091 or BIOS 20450 or SC 20450 or NSBH 20450)

BIOS 30341 Cell Biology (3 Credit Hours)

Designed primarily for junior preprofessional students. Structural and functional aspects of the biology of cells are addressed.

Prerequisites: ((BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202)) and (CHEM 10122 or CHEM 10172 or CHEM 10182 or CHEM 20273 or CHEM 20283)

BIOS 30342 Developmental Biology (3 Credit Hours)

Development of plants, animals, and microorganisms studied at the molecular, cellular, and organismic levels.

Prerequisites: (BIOS 20250 or BIOS 20303) and (BIOS 20241 or BIOS 30341)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 30344 Vertebrate (Human) Physiology (3 Credit Hours)

Physiological functions and processes at the level of organs and organ systems, oriented primarily toward humans.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202) and (CHEM 10122 or CHEM 10172 or CHEM 10182 or CHEM 20273 or CHEM 20283)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 30350 Introduction to Dynamic Models in Biology (3 Credit Hours)

Dynamic biological models can be powerful tools not only for prediction, but also for going beyond correlation and understanding causality. This course is designed to enable students to establish a strong background in the development, use, and interpretation of models. The course will focus on a set of case studies. The case studies will be drawn from diverse specialties, ranging from disease to forest ecology. The essential mathematical and programming techniques will be developed as needed to understand the modeling results. The relationship between models, experiments, and evaluation of biological hypotheses will be emphasized throughout.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202) and (MATH 10350 or MATH 10550 or MATH 10850) and (MATH 10360 or MATH 10560 or MATH 10092 or MATH 10091 or MATH 10860)

BIOS 30401 Principles of Microbiology (3 Credit Hours)

An introduction to microbial life, including structure and function of bacteria. Characterization and classification of microorganisms are considered and include their ecology, growth and death, metabolism, physiology, genetics and antigenic analysis. The impact of microorganisms on human health is discussed through representative pathogenic bacteria. Fall and/or Spring.

Prerequisites: (BIOS 10161 or BIOS 20201 or BIOS 10171) and (BIOS 10162 or BIOS 10172 or BIOS 20202) and (CHEM 10122 or CHEM 10172 or CHEM 10182 or CHEM 20273 or CHEM 20283)

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 30404 Vertebrate Biology (3 Credit Hours)

This biodiversity lecture (30404) and laboratory (31404) course will explore the biology of vertebrates, including their evolution, ecology, diversity, biogeography, systematics, morphology, physiology, behavior, and conservation. Lectures will cover major evolutionary trends in the structure, function, and diversity of vertebrates as well as the interrelationships among vertebrate groups. Laboratory will include detailed comparative study of representative vertebrates, survey of morphological diversity across many groups, and connections to cutting-edge research topics. There will also be multiple field trips, such as visiting the Shedd Aquarium and Field Museum in Chicago, the Potawatomi Zoo, bird watching, and herping!

Prerequisites: BIOS 10162 or BIOS 20202

Corequisites: BIOS 31404

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 30406 General Entomology (3 Credit Hours)

A study of the morphology, life histories, and systematic relationships of insects, with emphasis on medical and agricultural aspects. Alternating fall semesters.

Prerequisites: (BIOS 10162 or BIOS 20202)

Corequisites: BIOS 31406

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 30407 Animal Behavior (3 Credit Hours)

A consideration of individual and social behavior patterns, with emphasis on organization and adaptive significance. Neural, endocrine, genetic, and environmental factors modifying behavior will be examined. Spring.

Prerequisites: (BIOS 10162 or BIOS 20202)

BIOS 30408 Arthropods and Human Disease (3 Credit Hours)

Emphasis on physiology, genetics, and relationships of arthropods as agents and vectors of disease. Spring.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202)

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 30410 Cellular Neurobiology: Stem Cell to Disease (3 Credit Hours)

The nervous system is precisely organized to ensure that animals can react and learn from their environment. This task requires the coordination of numerous neural cell-types including but not limited to glial, immune, blood and neuronal cell populations. Coordinating these cells to make the mature nervous system requires such biological processes as intracellular signaling, cell-cell communication and cellular migration, proliferation and differentiation. Upon successful completion of this class, you will be able to describe how the single-cell zygote produces and organizes cells into a fully functional nervous system covering molecular and cellular events that contribute to such topics as neuronal differentiation, axon guidance, synaptogenesis, glial differentiation, glial ensheathment, immune cell production and brain-blood vessel development.

Prerequisites: BIOS 10171 or BIOS 10172

BIOS 30413 Behavioral Ecology (3 Credit Hours)

BIOS 30418 Medical Molecular Genetics (3 Credit Hours)

The course will introduce the tools of modern molecular biology and explore their applications at the frontiers of biological research. Advanced topics may include molecular medicine, biotechnology, development, evolution, and neurobiology. Fall.

Prerequisites: (BIOS 20250 or BIOS 20303 or BIOS 24250 or BIOS 24303) and (BIOS 20241 or BIOS 30341)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 30420 Aquatic Ecology (4 Credit Hours)

A study of the structure and function of aquatic systems with emphasis on the behavioral, physiological and morphological adaptations generated by the physical and chemical characteristics of various aquatic habitats. Fall.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202)

Corequisites: BIOS 31420

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 30423 Genomes: from variation to phenotypes to personalized medicine (3 Credit Hours)

This course will introduce the methods of genome science and explore their applications in biological research and their impact on biological thinking. Topics will include how genomes are studied, how they function, and how they evolve. The importance of comparative and functional genomics in identifying mechanisms of human diseases will be highlighted. Spring.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202) and (BIOS 20250 or BIOS 20303)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 30424 Tumor Cell Biology (3 Credit Hours)

This course is designed for undergraduate students interested in the biology of cancer. It will focus on understanding how normal cells become tumor cells and the specific molecular and cellular properties of tumor cells that are important for cancer progression. The course will also introduce the student to the field of cancer research through the critical examination of primary literature

Enrollment is limited to students with a major in Biological Sciences.

BIOS 30455 Medical Microbiology (3 Credit Hours)

This course provides an overview of basic principles in infectious disease caused by major microbial pathogens. Through lectures and discussion of assigned reading material, the course examines current and classical topics in the field of host-pathogen relationships with an emphasis on the interplay between pathogen strategies and the host response. Students will be expected to give group presentations on topics relevant to Medical Microbiology and participate in regular class discussions.

Prerequisites: BIOS 20241 or BIOS 24241 or BIOS 30341 or BIOS 34341

Enrollment is limited to students with a major in Biological Sciences.

BIOS 30456 Infectious Diseases: Biological Manifestations and Current Challenges (3 Credit Hours)

Since the earlier stages of human development, infectious diseases have play an important role in shaping our history. They have made great empires crumble to the ground and wiped out communities. From the ancient times, we have tried to understand these diseases to mitigate their effect in our society. This course will provide: 1) a historical perspective of infectious diseases; 2) how they impacted and shaped history; 3) the recognition of the causative agents and biological manifestations; 4) control methods throughout history; 5) modern infections; and 6) current methods of prevention, treatments, and challenges.

BIOS 30465 Herpetology (3 Credit Hours)

This biodiversity course will explore the biology of living amphibians and reptiles, including their evolution, ecology, diversity, biogeography, systematics, morphology, physiology, behavior, and conservation. Lectures will include hands-on activities to promote "practical herpetology" skills and connections to cutting-edge research topics and approaches in the field of herpetology.

BIOS 30550 Foundations of Global Health (3 Credit Hours)

Over the last two decades, there has been a groundswell of interest in global health across multiple disciplines and professional fields. The field of global health recognizes the multidimensionality of health as well as the interconnectedness of everyone living in the world today; its primary goal is to eliminate health disparities to achieve health equity for all. This course will provide foundational knowledge necessary to understand what global health is today; its history and evolution; how social theory contributes to understanding specific global health problems; the importance of understanding health and designing interventions by using a biosocial model that includes a myriad of cultural, social, political, economic factors; and an understanding of the role of various actors on the global health stage including international, bilateral, and civil society organizations.

BIOS 31312 Practical Ecology Laboratory (2 Credit Hours)

Practical Ecology provides experience with essential procedures used in ecological science. Over the semester, students practice the science of ecology by participating in three study topics, both in the field and laboratory. During these practical exercises, students study local ecosystems to understand how, through important ecological processes, those ecosystems are built and operate. Students gain the foundational knowledge for advanced practical coursework and undergraduate research in ecology and environmental sciences, including design of experiments and surveys, sampling and measurement, analysis of data, and scientific writing. Students are advised to take the course either with or after taking General Ecology.

Prerequisites: BIOS 30312 (may be taken concurrently)

Enrollment is limited to students with a major in Biological Sciences, Environmental Sciences or Environmental Sciences (Supp.).

BIOS 31341 Cell Biology Laboratory (1 Credit Hour)

This laboratory course exposes students to a variety of techniques in modern cell biology. Students will get hands-on experience in working with cultured cell lines, including sterile technique, media preparation, and passaging of cells. Individual experiments will include assessment of cell growth and apoptosis, examination of subcellular structure using fluorescent microscopy, separation and analysis of nucleic acids and proteins, enzyme assays, and measurement of cell cycle by flow cytometry. It provides an excellent introduction to the approaches routinely used in analysis of cells and their functions. Fall.

Prerequisites: BIOS 20241 or BIOS 30341 (may be taken concurrently) or BIOS 24241 or BIOS 34341

Enrollment is limited to students with a major in Biochemistry or Biological Sciences.

BIOS 31401 Principles of Microbiology Lab (1 Credit Hour)

Laboratory exercises consider basic techniques in microbiology, such as sterile procedures and microbial metabolism. Fall.

Prerequisites: (BIOS 30401 (may be taken concurrently)) and (BIOS 10162 or BIOS 10172 or BIOS 20202)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 31404 Vertebrate Biology Laboratory (1 Credit Hour)

Corequisites: BIOS 30404

BIOS 31406 General Entomology Laboratory (1 Credit Hour)

The laboratory introduces students to insect morphology, systematics, and techniques used in the study of insects. Offered concurrently with lecture.

Prerequisites: BIOS 30406 (may be taken concurrently)

Corequisites: BIOS 30406

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 31408 Arthropods and Human Disease Lab (1 Credit Hour)

The laboratory introduces students to the variety of arthropods that vector disease agents or otherwise affect the lives of humans and other vertebrate animals. Offered concurrently with lecture.

Prerequisites: BIOS 30408 (may be taken concurrently)

BIOS 31420 Aquatic Ecology Laboratory (0 Credit Hours)

Aquatic ecology laboratory is to be taken concurrently with the aquatic ecology lecture. Students may not take lecture alone or laboratory alone.

Prerequisites: BIOS 30420 (may be taken concurrently)

Corequisites: BIOS 30420

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 32318 Intro to Biocomputing Tutorial (0 Credit Hours)

Tutorial for BIOS 30318

Corequisites: BIOS 30318

BIOS 33201 Geographic Information Systems (3 Credit Hours)

This course is aimed to provide a basic understanding of how Geographic Information Systems (GIS) and satellite imagery can be used to visualize and analyze environmental data. Students will learn basic techniques for analyzing, manipulating and creating geospatial data in both pixel-based (satellite imagery and digital terrain models) and vector based (point, line and polygon representation of spatial data) formats. Students will also learn how acquire high resolution satellite imagery and other GIS data from online data servers.

BIOS 34425 Tumor Cell Biology (3 Credit Hours)

Prerequisites: BIOS 10172

BIOS 35501 Introduction to UNDERC (1 Credit Hour)

Open only to students previously accepted into the UNDERC program.

Course may be repeated.

BIOS 35502 Practicum in Environmental Field Biology (3 Credit Hours)

Course modules include vertebrate ecology, invertebrate ecology, aquatic ecology and forest ecology with each providing background information, field research exercises, and group research projects designed by the class. Five or more weeks are spent by each student designing and conducting their own field research project under direction of faculty or graduate students.

BIOS 35503 Practicum in Environmental Biology West (3 Credit Hours)

This course is designed to give the student advanced practical laboratory experience in ecological studies in the grasslands and mountains of western Montana on the Flathead Indian Reservation. The ten week learning experience consists of one week modules on grassland/wildlife ecology, montane ecology, and human ecology focusing on ancestral Native American lifeways, and each student conducts an independent research project over the remaining weeks

Prerequisites: BIOS 35502

BIOS 35504 Research Projects in Field Environmental Biology (1-3 Credit Hours)

An independent research opportunity offered to undergraduates that have had at least one summer or semester of summer research experience. The research will be conducted at the University of Notre Dame Environmental Research Center (UNDERC). An UNDERC-affiliated scientist mentors each student on the development of a research proposal, implementation of the project, analyses of the data collected and the writing up and presentation of the project at the end of the summer. Past projects have ranged from behavioral, population, community and ecosystem ecology to local Native American ecosystem use.

BIOS 35506 Practicum in Field Environmental Biology-Galapagos Islands (2 Credit Hours)

During an ~8-day field trip to the Galápagos archipelago during an intersession period (Fall break or Spring break), this course will introduce and amplify principles of evolutionary biology, ecology, and environmental science that occur in the unique setting of the famed Galápagos Islands. Pre-trip meetings will emphasize background knowledge important to understanding the unique features of the archipelago as they have influenced evolutionary and ecological theory. On-site lectures and activities will cover the historical, geological, and biological features of the archipelago. The trip will include visits to the Charles Darwin Research Station and several scientifically significant sites in the Galápagos archipelago. Post-trip meetings will summarize the major discoveries of the trip as presented by the students. Prerequisites for this practicum include an approved course in evolutionary biology, chosen from among BIOS 30305 or 30310, which may be taken concurrently with this course. Because space is limited to 14 students, permission of the instructors is also needed to enroll in the course. This course is open to any Notre Dame undergraduate. The field trip to the Galápagos is optional, it is not an alternate to class requirements, and it is not a means of earning extra credit in the course.

Prerequisites: BIOS 30305 (may be taken concurrently) or BIOS 30310 (may be taken concurrently) or BIOS 30312 (may be taken concurrently)

BIOS 36495 Junior Biological Sciences Honors Research Seminar (1 Credit Hour)

The Honors program will give students an exceptional background in biological research. Participation in this program will increase their level of commitment and productivity while preparing them for successful postgraduate careers. The goals of the Junior Honors seminar are to: 1) Critically evaluate research data, 2) Design scientifically defensible experiments and projects, 3) Create and present a professional research talk or poster, 4) Articulate career goals following career exploration, 5) Identify common research ethics issues and articulate solutions to these issues, 6) Write a research proposal or report supported by primary literature.

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 37492 Teaching Practicum in the Life Sciences (0-1 Credit Hours)

Similar to BIOS 37493 except that this is an S/U-graded zero credit section.

Course may be repeated.

BIOS 37493 Teaching Practicum in the Life Sciences (0-2 Credit Hours)

Same as BIOS 37495 except that this is a s/u variable credit section; 2.0 maximum credits allowed.

Course may be repeated.

BIOS 37494 Teach Practicum/Life Sciences (1-2 Credit Hours)

Same as BIOS 37495 except that this is a letter-graded variable credit section; 2.0 maximum credits allowed

Course may be repeated.

BIOS 37672 Special Studies (1-4 Credit Hours)

Special topics in the field of interest for individual or small groups of undergraduate students or for the one-time introduction of new course materials will be covered. Spring. Repeatable course.

Course may be repeated.

BIOS 40132 Introduction to Computational Genomics (3 Credit Hours)

Dive into the Code of Life: Computational Genomics! This exciting course provides a comprehensive introduction to modern genomics analysis, designed for senior undergraduate and graduate students. Students will gain hands-on experience in processing and interpreting complex genomic datasets, focusing on three core modules: Genomics Quality Control (QC), Bulk RNA-seq analysis, and Single-Cell RNA-seq analysis. The course emphasizes the development of essential bioinformatics skills and the use of cutting-edge software tools to explore biological data. Throughout the course, students will apply their knowledge to real-world datasets, culminating in module-based projects that showcase their analytical and presentation skills. This course aims to equip students with the necessary tools and knowledge to tackle contemporary research questions in genomics, fostering critical thinking and data interpretation skills.

BIOS 40200 Unlocking the Secrets of Rare Cancers: Mutations and Targeted Therapies (3 Credit Hours)

This course will provide students with in-depth understanding of the research involved with development of targeted therapies for rare cancers. Through lectures by faculty experts, active discussion, and group work, students will develop skills to evaluate the clinical presentation of rare cancers, assess the effects of specific mutations on cancer cells and their regulatory networks, and investigate current treatments and novel targeted therapies based on this information to propose potentially effective treatments for patients. Prior completion of CHEM 40420 strongly encouraged.

BIOS 40202 Developmental Neuroscience: Experience Dependent Plasticity (3 Credit Hours)

This is an upper level NSBH biology elective that is also a community-based learning course. Through reading and discussion of primary literature, the developmental literature will offer students an opportunity to investigate and construct conceptual frameworks of the circuitry that underlies human species expectant experiences. Using the expectations of the developing nervous system as the guiding framework, class and community work will explore how individual experience becomes a powerful moderator of the nervous system function as we age. The community-based aspect of the course partners students with organizations that are engaged with the regional Self-Healing Communities Collective; a community-capacity building network that uses neuroscientific evidence to inform organizational and community strategies supporting neurobiological safety and resilience. Success in this course requires consistent time and engagement every week in class and can be well suited for students wishing to explore intersections of neuroscience, plasticity, health, behavior and well-being.

Prerequisites: (BIOS 10161 and BIOS 11161 or BIOS 20201 and BIOS 21201) and (BIOS 20450 or BIOS 30338 or BIOS 30339 or SC 20450)

Satisfies the following University Core Requirements: WRIT - Writing Intensive

BIOS 40203 Neuroinfectious Diseases (3 Credit Hours)

Despite the advancement achieved in the last few decades fighting various infectious diseases (smallpox, polio, malaria, active tuberculosis, syphilis), infections of the central nervous system still are the ones with the highest morbidity and mortality. This course will review the reasons why treatment of these infectious diseases is so challenging: the physiology of our anatomy, the mechanisms exploited by neuropathogens, and recent medical advancements that ironically, makes us susceptible to these diseases. Lastly, certain non-infectious neurological conditions share pathological features with that of infectious agents. These will be compared and their potential treatments discussed based on their similarities.

BIOS 40309 Biogeochemistry and Ecosystem Ecology (3 Credit Hours)

The course will examine the interacting processes of the physical environment and the biota as they influence the flux and distribution of chemical substances in the biosphere (i.e. biogeochemistry & ecosystem ecology). The course will also explore major chemical, biological, and geological processes that occur within and between terrestrial and aquatic ecosystems at the scales of organisms, functional groups, ecosystems, and the globe. The course is open to upper-level undergraduates with a strong interest in ecology and environmental biology and who have had a minimum of one semester of ecology (i.e., general ecology, aquatic ecology). Offered on demand.

BIOS 40310 Cancer Immunotherapy (3 Credit Hours)

Immunotherapy, believed to be the most promising new form of cancer treatment since the emergence of chemotherapy, is now being celebrated as a top advancement in cancer care. Tremendous advances in biological mechanisms underlying tumor immunology started to guide the development of successful new cancer immunotherapy strategies after decades of bewildering disappointments. This course will introduce the advanced undergraduate students and early career graduate students to the basic principles of tumor immunology and immunotherapy, classical and novel classes of treatment that enhance anti-tumor immunity, and recent progresses in treating a number of highly lethal cancer types with immunotherapy. The course will also teach the students how scientists have achieved the groundbreaking landmark discoveries in tumor immunology and immunotherapy through critical examination of primary literature. At the completion of the course, the students should have had a comprehensive grasp of the key principles and practices of cancer immunotherapy, and gained the ability to interpret new advances and breakthroughs in this field. Students with goals in both basic research and medical track will benefit from the course.

Prerequisites: BIOS 20241 or BIOS 24241 or BIOS 30341 or BIOS 34341

BIOS 40339 Human Gross Anatomy (3 Credit Hours)

Prerequisites: (BIOS 10161 and BIOS 11161 and BIOS 10162 and BIOS 11162) or (BIOS 20201 and BIOS 21201 and BIOS 20202 and BIOS 21202)

BIOS 40340 Human Anatomy (4 Credit Hours)

The course will consist of a description of human gross anatomy. The content will be organized as a regional approach to gross human anatomy with descriptions of the back, thorax, abdomen, pelvis and perineum, lower limb, upper limb, and head and neck. Within each region, subtopics will include bones, ligaments, muscles, vasculature, lymphatics, peripheral nervous system, and regional viscera. The content emphasis will be basic human anatomy although there will be a moderate amount of clinical anatomy. The required laboratory portion of the course will consist of regional dissection of partially dissected human cadavers, as well as identification of structures of previously dissected human cadavers. The course should serve as a foundation for students planning future human anatomy studies and/or an independent elective. Spring.

Corequisites: BIOS 41340

Enrollment is limited to students with a major in PreProfessional Studies, Biological Sciences, Science- Business or PreProfessional.

BIOS 40411 Biostatistics (4 Credit Hours)

Basic principles of statistical analysis and their application to biological problems, including statistical inference, analysis of variance, regression, non-parametric approaches, and introduction to statistical computing. This course's "lab" is a tutorial; it does not fulfill the laboratory elective requirement (after 1993). Students may not take both BIOS 40411 and MATH 20340. Spring.

Prerequisites: (BIOS 10162 or BIOS 20202) and (MATH 10360 or MATH 10560 or MATH 10092 or MATH 10860 or MATH 10460)

Corequisites: BIOS 42411

Satisfies the following University Core Requirements: WKQR- Core Quantitat Reasoning

Enrollment is limited to students with a major in Biological Sciences, Environmental Sciences or Environmental Sciences (Supp.).

BIOS 40412 Introduction to Systems Biology (3 Credit Hours)

The goal of this course is to illuminate the elementary design principles inherent in biology. Many of the underlying principles governing the network of biochemical reactions in a living cell can be related to circuit motifs with multiple inputs/outputs, feedback and feedforward. This course draws on control theory, elementary chemistry and first-year calculus to provide a framework to discover and understand the performance of these networks. The topics examined in the course are drawn from current research and include: transcription networks, stochastic gene expression, adaptation, oscillators (circadian rhythms and the cell cycle), metabolism, pattern development, neural networks and cancer. The course is intended for advanced undergraduates in biology and engineering, but will appeal to graduate students as well. (Prerequisite course: elementary chemistry (a course such as CHEM 10171 OR CHEM 10181); Recommended courses: elementary calculus (a course such as MATH 10560 may be taken concurrently); OR linear algebra and differential equations (a course such as MATH 20580 may be taken concurrently.)

Prerequisites: CHEM 10171 or CHEM 10181

Enrollment is limited to students with a major in Biological Sciences.

BIOS 40414 The Biology of Stem Cells and the Emerging Field of Regenerative Medicine (3 Credit Hours)

This course will examine the biology of stem cells and explore their uses and applications of stem cells.

Prerequisites: BIOS 20241 or BIOS 24241 or BIOS 30341

Enrollment is limited to students with a major in Biological Sciences.

BIOS 40415 Medical and Veterinary Parasitology (3 Credit Hours)

The animal parasites of humans and related hosts are reviewed. The pathology caused by these parasites, epidemiology, life cycles, prophylactic and therapeutic control are considered. Spring.

Prerequisites: (BIOS 10161 and BIOS 10162) or (BIOS 10161 and BIOS 20202) or (BIOS 20201 and BIOS 20202) or (BIOS 20201 and BIOS 10162)

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 40416 Virology (3 Credit Hours)

A study of viruses as primitive biological entities and as disease-inducing agents in humans and other animals: characteristics of viruses and virus infections; molecular aspects of virus replication; methods for diagnosis and prevention of infections; artificial use of viruses. Spring.

Prerequisites: (BIOS 20250 or BIOS 20303) and (BIOS 20241 or BIOS 30341) and (BIOS 21250 or BIOS 21303) and (BIOS 31341 or BIOS 27241)

BIOS 40419 Immunology (3 Credit Hours)

In this course we will cover one of the most interesting biological systems in you…the immune system! We will cover the different types of immune responses, how they are triggered by exposure to foreign microbes or in response to the presence of tumors. We will also discuss what happens when the immune system goes wrong leading to autoimmune diseases. Finally, we will cover how we can use immune modulation as a mechanism to treat various diseases. The course will use a mix of text-book information, lectures, videos and primary research articles to cover the material.

Prerequisites: (BIOS 10162 or BIOS 20202) and (BIOS 20250 or BIOS 20303) and (BIOS 20241 or BIOS 30341)

Enrollment is limited to students with a program in Pre-Health Studies (Supp.), Biochemistry, Biological Sciences, Science- Business or PreProfessional.

BIOS 40420 Molecular Epidemiology of Infectious Diseases (3 Credit Hours)

In a world ever more connected, and inhabited by an increasing human population, the number of infectious disease outbreaks is rising. Understanding the epidemiology of viruses, bacteria, and parasites is crucial for the design of strategies to interrupt transmission. In the last two decades, molecular methods to study DNA, RNA, proteins, and antibodies have increasingly been used for such studies. Diagnosis by molecular tools increases the sensitivity over traditional methods such as microscopy. The genetic diversity of the pathogen and the host can be exploited to identify genes responsible for drug resistance, or to establish transmission networks. Antibody measurements allow the study of the human response to infection. This course will provide an overview of current laboratory methods to study infectious disease dynamics and discuss examples from the literature.

Prerequisites: (BIOS 20241 or BIOS 30341)

BIOS 40425 Mammalogy (4 Credit Hours)

This course will explore the rich taxonomic diversity of mammals, and investigate mammalian physiology, ecology, and behavior. Students will use a general text for foundation and implement their learning experience with primary literature.

Prerequisites: (BIOS 10162 or BIOS 20202)

Corequisites: BIOS 41425

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 40427 The Epidemiology and Ecology of Infectious Diseases (3 Credit Hours)

This course will introduce students to basic principles of the epidemiology and ecology of infectious diseases, familiarize students with mathematical and statistical modeling approaches for applying those principles to data, and provide students with opportunities to use empirical data to apply those approaches. This course will involve programming in the R computing language.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 40436 Introduction to Molecular and Medical Pharmacology (3 Credit Hours)

This course will cover the general principles of pharmacology and the molecular and cellular mechanisms of action of various drugs. The major topics covered will be drugs affecting the nervous system, drugs affecting the cardiovascular system, drugs treating cancer, and the major steps involved in new drug development in the pharmaceutical industry. We will also discuss pharmacogenomics, an emerging field of medical research and application in the post-genomic era

Prerequisites: BIOS 30344 and (CHEM 40420 or CHEM 30341)

BIOS 40450 Introduction to Science and Patient Advocacy (3 Credit Hours)

A main purpose of this course is to engage upper level undergraduate and graduate students in clinical research in rare and neglected diseases. The focus for each semester is on neglected/infectious diseases with emphasis on worldwide eradication strategies. A major goal is to have Notre Dame students work on a clinical research project in class on some rare and/or neglected disease of major importance. A second important goal of this course is to develop an analogous model(s) for other neglected/infectious diseases. We hope this class will also help the students become advocates for these diseases. The course is also tied to a clinical-translational seminar series to enable students to meet with leading international experts who work in neglected diseases. The class is intended for juniors and seniors.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202)

BIOS 40451 Rare Disease Advocacy Immersion (1 Credit Hour)

Students in the Minor in Science and Patient Advocacy program will participate in a community-based experience that incorporates the academic context gained from the minor gateway courses and applied to a patient advocacy project that fulfills a patient, family, or community need. The student will engage with site partners to outline objectives and discuss how their engagement and participation will meet the overall learning objectives of the Minor. This engages the student in active participation in "real life" experiences of patient advocacy and provides a learning experience unique to this minor program Students will learn/course will address: - Understand and develop tools for effective patient advocacy - Understand the overall challenges faced by rare disease patients - Build relationships with community organizations that promote advocating for patients - Identify a patient unmet need in the community and apply the skills acquired from minor gateway coursework to advocate for patient and family

BIOS 40491 Current Topics in Environmental Science (3 Credit Hours)

Taught by the Director of the ES major. Environmental sciences first and second majors only. The course will be divided into various modules taught by experts on and off-campus. The modules will include environmental law, risk assessment, environmental ethics, advancements in environmental science, current topics of national interest in environmental science, and others. This course is required of all first majors and recommended of all second majors. Fall.

BIOS 40500 Translational Research: bringing lab work into the clinic (3 Credit Hours)

In this course, we will discuss important basic science results that have led to impactful human therapeutics, and we will take you through the process of taking a method/product from the “bench to bedside.” In the first part, we will use classical and current primary literature to discuss the rationale, technologies, and models developed in the discovery of a variety of products designed to improve health. The second part will provide the students with a clear understanding of the concepts of translational research, including the steps post-research, namely, invention disclosure, patent protection, searching for investors, and commercialization. Both parts work together as the students will come up with their ideas on the first part, based on the topics discussed, and then work on developing their ideas on the second part, culminating with a final presentation of their product.

BIOS 40507 Epigenetics: Genetics, Ecology, and Plasticity (3 Credit Hours)

Have you ever wondered how a single cell could possess all the genetic information in an organism but only display certain phenotypic traits? Have you ever questioned how genetically identical organisms can be morphologically distinct under certain conditions? Have you noticed how the environment can induce aberrant gene expression resulting in disease, including reproductive disease in humans that can be transmitted across generations? Epigenetics: Genetics, Ecology, and Plasticity covers the emerging field of epigenetics, detailing mechanisms and their understood functions. The course applies epigenetic knowledge to evolutionary concepts, like phenotypic plasticity, demonstrating how environmental stimuli can incite change within- and across generations. The course assesses how these changes can remain within a population, resulting in a new phenotypic trait that changes how humans see and interact with the organism. Finally, the course 1) provides model organisms for studying epigenetics, 2) challenges students to formulate a hypothesis to address how an organism could respond epigenetically to an environmental change, and 3) explain how their hypothesis would work by synthesizing information given in this course and the prerequisites listed.

BIOS 40508 Population Genetics (3 Credit Hours)

This course will describe and mathematically analyze the processes responsible for genetic change within populations. See Graduate Bulletin of Information

BIOS 40522 GLOBES: Humans, Genes, and the Environment (3 Credit Hours)

Globally humans inhabit and alter landscapes creating anthropogenic ecologies impacting all resident organisms. The distribution and structuring of genomes, the movement and virulence of pathogens, and the patterns of coexistence of organisms are all interconnected at multiple levels.This course focuses on the dynamic transactions between organisms and environments at multiple levels, with a specific consideration of impacts on health, interspecies interfaces, and population genetics. It considers theoretical perspectives and specific examples from population genetics, ecology, evolutionary biology, anthropology, and political ecology to examine scenarios of interaction between humans, genes, and the environment.

Course may be repeated.

BIOS 40524 Global Change and Civilization (1-3 Credit Hours)

All human populations, from the simplest to the most complex, interact with their natural environment. Humans alter the environment and, in turn, are altered by it through biological or cultural adaptations. Global environmental chanages helped to create and shape our species, and modern industrial societies are capable of altering the environment on scales that have never been seen before.This course explores the ways that humans are altering the global environment and the ways that global environmental changes alter humans in return. Students will complete the course with an understanding of the metrics and physical science associated with each type of change, their ecological implications, and the ways in which environmental changes continually reshape human biology and culture.

BIOS 40525 Community Ecology (3 Credit Hours)

Community ecology is the study of the direct and indirect interactions among species and the environment that determine the structure, abundance, and composition of communities. Foundational topics within the field of community ecology include: ecological and evolutionary processes that create, maintain or modify patterns of biodiversity; the relationship between biodiversity and ecosystem function; island biogeography; metacommunity dynamics; niche and neutral theory; species interactions (e.g., competition, predation, and mutualism) and species coexistence; and effects of natural- and human-mediated environmental change (e.g., climate change, habitat alteration, invasive species) on biodiversity. As such, central concepts and theories in community ecology have also shaped our understanding of related fields, including population, ecosystem, and evolutionary ecology. Through discussion of foundational literature and related contemporary papers, this course seeks to provide graduate and advanced undergraduate students a broad overview of the central concepts of community ecology, as well as an appreciation for how these ideas have changed over time and inspired ongoing research.

BIOS 40527 Stream Ecology (4 Credit Hours)

This course explores the interaction of biological, chemical, and physical features of streams and rivers. Human impacts on flowing waters are explored, along with current theory of stream ecology.

Corequisites: BIOS 41527

BIOS 40528 Global Change Biology: Ecosystems, Society, and Health (3 Credit Hours)

Humans have had a profound impact on the environment since the beginning of recorded history. Humans have modified ecosystems, altered waterways and oceans, impacted the chemical composition of Earth’s atmosphere, changed the geography of organisms and diseases, and built societies that are reliant on the modification of natural ecosystems. Many of these activities have resulted in unsustainable practices that threaten the future biosphere and human societies. In this class, we will explore the many facets of human (i.e. anthropogenic) impacts on Earth’s biosphere as well as the impact to ecosystem services that humanity depends on to thrive. The course will mostly focus on the impacts of industrialization and global climate change on the current and future functioning of the biosphere and human society. The course will be organized into five modules that cover human impacts from the level of the individual organism to the biosphere and human society. The course will end with the current state of environmental and engineering solutions to minimize our impact on the environment.

BIOS 40550 Topics in Pathobiology: Personalized medicine (2 Credit Hours)

The primary purpose of this course is to introduce current and emerging technologies in scientific research with a specific focus on concepts relevant to precision-based individualized medicine. Examples will include- personalized genome analysis and GWAS, metabolome and microbiome studies, genetic basis of rare disease disorders, and biochemical aspects of mechanisms of rare disease. The overall format for this class will be a detailed discussion of highlighted journal articles relevant to the topic discussed. This class will meet once weekly and will be open to both juniors and seniors enrolled in the minor program. This class will also include graduate students interested in advanced topics of research. Having a class composition of both undergraduate and graduate students is a particular strength of this course, as it maintains a standard of rigor typical of an advanced level class.

BIOS 40552 Bayesian Statistics and Biological Forecasting (3 Credit Hours)

Forecasts incorporate data and models (our ideas of how biological systems work) to produce predictions, and are thus both useful for both applied (a COVID forecast) and basic (hypothesis testing) biology. It will help to have some experience coding in R (or another language), but if you've got moxie you can pick this up along the way.

BIOS 40565 Topics in Rare Disease Advocacy and Policy (1-3 Credit Hours)

The main purpose of this advanced biology course is to engage undergraduate students in clinical research and patient advocacy in rare diseases. BOIS 40565 is the capstone course for the Minor in Science and Patient Advocacy but those students not enrolled in the minor are welcome to take this course with approval.

BIOS 40568 Malaria Control (3 Credit Hours)

Malaria remains to be one of the deadliest infectious diseases globally. After a first, failed attempt to eliminate the parasite in the 1960ies, the world aims again for malaria elimination. In this class, we will discuss different strategies for malaria control and elimination. We will assess strategies that target the parasite and/or the vector, and will talk about the recently approved malaria vaccine and other vaccine developments. We will discuss case studies of countries that succeeded in malaria eradication, and talk about the financial aspects of different control strategies. After completing this class, you will have a comprehensive understanding of different strategies for malaria control, elimination, and prevention of reintroduction to malaria-free regions.The class will focus on reading and discussing original research papers and reviews. Students will prepare presentations, and discus papers with the class.

BIOS 40571 Topics in Physiology (1-3 Credit Hours)

Consent of instructor to enroll. Subject matter changes depending on students' needs. Prospective subjects include invertebrate and vertebrate physiology. (On demand)

BIOS 40572 Clinical Research Rare & Neglected Diseases (3 Credit Hours)

BIOS 40573 Restoration Ecology (3 Credit Hours)

This course focuses on the ecological principles that underlie ecosystem restoration and the evaluation of actual restoration efforts with case histories. We give balanced attention to terrestrial (e.g., forests, prairies, arid lands) and aquatic ecosystems (e.g., lakes, streams, wetlands, estuaries). The format is lecture/discussion of current literature, and each student leads the discussion of several papers over the course of the semester. The goals of the course are (1) to familiarize students with the theory and practice of ecosystem restoration, (2) to understand the ecological basis of restoration, and (3) to evaluate examples of restoration from terrestrial and aquatic ecosystems.

BIOS 40580 Neurobiology of Pain (3 Credit Hours)

This course will provide students with a background on the biological basis of pain. The course will not only explore tradition pain pathways and the contribution of inflammatory mechanisms in the perception of pain, but also consider how factors such as emotions, memories, and prior painful experience contribute to the neural processing of pain. Students will examine how different neurobiological pathways and functional systems contribute to the complexities of pain sensation and come to understand that specific injuries do not indicate specific levels of pain. In addition, clinical pain models and pharmacological/non-pharmacological treatments of pain will be discussed.

BIOS 41340 Human Anatomy Laboratory (0 Credit Hours)

This laboratory consists of regional dissection of partially dissected human cadavers, as well as identification of structures of previously dissected human cadavers. The course should serve as a foundation for students planning future human anatomy studies and/or an independent elective. Spring.

Corequisites: BIOS 40340

Enrollment is limited to students with a program in Pre-Health Studies (Supp.), Biological Sciences, Science- Business or PreProfessional.

BIOS 41344 Vertebrate (Human) Physiology Laboratory (1 Credit Hour)

This laboratory provides students the ability to investigate physiology by asking them to demonstrate hands-on application of physiological concepts through identification of anatomical structures, utilizing the scientific process and clinical techniques to delve into physiological processes, and communicating across multiple scientific formats to explain how the processes of an individual system, and what governs integrated body function.

Prerequisites: (BIOS 30344 or BIOS 30421) or BIOS 34344 or BIOS 40421

Enrollment is limited to students with a major in Biological Sciences.

BIOS 41415 Medical and Veterinary Parasitology Laboratory (1 Credit Hour)

The laboratory introduces students to the microscopic world of parasites. Extensive microscope work is needed. Spring, on demand.

Prerequisites: BIOS 40415 (may be taken concurrently)

Enrollment is limited to students with a major in Biological Sciences.

BIOS 41425 Mammalogy Laboratory (0 Credit Hours)

In conjunction with Mammalogy lecture, this course will provide a hands-on experience in the study of mammals, including how to capture and identify mammals, some unique aspects of mammalian physiology, and use of the scientific method to understand mammalian ecology and behavior.

Corequisites: BIOS 40425

Enrollment is limited to students with a major in Biological Sciences or Environmental Sciences.

BIOS 41527 Stream Ecology Laboratory (0 Credit Hours)

Quantitative analysis of stream biota and periodic physical features is conducted during field laboratory sessions.

Corequisites: BIOS 40527

BIOS 42411 Biostatistics Tutorial (0 Credit Hours)

The biostatistics tutorial is to be taken concurrently with the lecture. Students may not take lecture alone or the tutorial alone.

Corequisites: BIOS 40411

BIOS 46490 Biological Sciences Honors Research Seminar (1 Credit Hour)

One or more seminars in a select discipline(s) will be offered every semester and is required of all participating in the biological sciences research honors program. The purpose of these disciplinary groups is to create a small learning community where students and practicing scientists can connect. The seminar learning goals are to support and develop each student's independence, scientific communication skills, critical review skills, and understanding of their research in the context of the larger field. As appropriate, the groups will meet as a whole to foster interdisciplinary habits of mind and skills. The seminar will have the added benefit of helping students prepare for graduate applications and fellowships.

Course may be repeated.

Enrollment is limited to students with a major in Biological Sciences.

BIOS 46494 Directed Readings Environmental Sciences Opinion Editorials (1 Credit Hour)

The purpose of the Directed Readings Environmental Sciences Opinion Editorials course is to give students a better understanding of the process of writing Opinion Editorials about Environmental Sciences issues. There is already a long-standing tradition of experts writing Opinion Editorials to affect change but this can be a difficult medium for science professionals to master given the contrasting nature to the usual technical writing in the discipline. Students will meet one to two hours a week at a mutually convenient time and place to discuss existing, published Opinion Editorials and then use those discussions to revise and update the Opinion Editorials they have already produced during their participation in the ES major capstone course, Current Topics in Environmental Sciences. The revisions of their Opinion Editorials will take place in their own time.

BIOS 46497 Directed Readings (1-3 Credit Hours)

This course provides the opportunity for independent study through readings on specific topics in biological science. Readings are chosen with the advice of the supervising instructor. Students may not register for more than three credits per semester; only two credits per semester may be counted as BIOS elective credits by majors. Offered all semesters.

Course may be repeated.

BIOS 47500 Principles of Comparative Medicine and Surgery (3 Credit Hours)

An introduction to comparative medicine and experimental surgery. In this regard, the responsible and humane use of animals as a means to understand and grow knowledge and principles which form the foundation of human and animal medicine represents core knowledge for physicians and other health professionals, scientists, and veterinarians. This course will provide students with background on the use of animal models in the study of human and animal disease, particularly in the areas of infectious disease, cancer, and pharmaceutical discovery. Further, general concepts and basic principles for surgery, including anesthesia, aseptic technique, management of the surgical patient, tools of the surgeon, and suturing and wound closure techniques will be covered.

Prerequisites: (BIOS 10161 or BIOS 20201) and (BIOS 10162 or BIOS 20202) and BIOS 30344

BIOS 48498 Undergraduate Research (0-3 Credit Hours)

Research in collaboration with members of the faculty. Evaluation of performance will be accomplished through regular discussions with the faculty member in charge of the course. Enrollment must be completed before the end of the first week each semester. Students may not register for more than three credits per semester; only two credits per semester may be counted as BIOS elective credits by majors. Offered all semesters.

Course may be repeated.

BIOS 48499 Undergraduate Research (0-10 Credit Hours)

Course may be repeated.